We are encountering more people in our friends and family circle who have been touched by Cancer. The answer that it “runs in my family” is becoming more common as we take a family history from a new patient. Even in my own family, I can now count 2 maternal first cousins who have been treated for breast and ovarian cancer in their 30s and early 40s, in addition to several older extended family members. There are very few identifiable genetic mutations that would explain this rise in the visibility of cancer around us. In the older population, one can say that overall life expectancy has increased, so instead of succumbing to acute cardiac events, we are living longer, and succumbing to cancer related illnesses. In addition, our bodies have then been exposed to environmental noxious agents inadvertently or not, for a longer period of time.